Worldwide, more than half a billion women of reproductive age are anaemic. Each year, about 70 000 women who give birth die from postpartum haemorrhage. Almost all deaths are in low-income or middle-income countries. We examined the association between anaemia and the risk of postpartum haemorrhage.


  • We did a prospective cohort analysis of data from the World Maternal Antifibrinolytic-2 (WOMAN-2) trial. 
  • The trial enrolled women with moderate or severe anaemia giving birth vaginally in hospitals in Pakistan, Nigeria, Tanzania, and Zambia.
  • Anaemia is strongly associated with postpartum haemorrhage and the risk of death or near miss. 
  • Attention should be given to the prevention and treatment of anaemia in women of reproductive age.

How to Use

The paper explores the crucial link between maternal anaemia and postpartum haemorrhage, while demonstrating the potential of tranexamic acid as a lifesaving intervention.