Driving Global Adoption: A Comprehensive Guide for Implementing WHO’s Revised Recommendation on Uterotonics for PPH Prevention, Leveraging Smiles for Mothers’ Experience in Nigeria


  • The program supported the 3 states to implement costed roadmaps for the adoption and roll-out of medicines aligned with WHO recommendations on the use of uterotonics to prevent postpartum hemorrhage, including introducing a new uterotonic, heat-stable Carbetocin.
  • The Smiles for Mothers program is committed to improving the quality of care for the prevention of PPH in public health facilities and reducing mortality due to PPH using a system-strengthening approach that covers patient literacy and community awareness, supply chain management, and service delivery. 
  • Over the two-year implementation period from 2020 to 2022, significant progress was made, and the Smiles for Mothers Playbook is a culmination of that journey.

How to Use

The playbook serves as a valuable reference tool for healthcare professionals, policymakers, and stakeholders involved in maternal health initiatives. It provides guidance on the adoption and rollout of the WHO recommendations on uterotonics for the prevention of PPH, including the introduction of heat-stable Carbetocin.